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Why AI Isn’t Ready to Tackle Our Convoluted Genomes
The DNA inside our cells isn’t just a series of instructions, but something far more dynamic. Like scientists, AI models don't yet have the data to properly decode it.

HDFC Bank Q2 Results: Net profit rises 5% to ₹19,610 crore, NII jumps 10% in last quarter under outgoing CEO Jagdishan
HDFC Bank reported a 5.2% year-on-year rise in standalone net profit to ₹19,609.96 crore in Q2 FY27. Net interest income increased 9.72% to ₹34,619.18 crore, while gross and net bad-loan ratios stood at 1.11% and 0.37%, respectively.
10 smallcap stocks surge up to 65% in 3 months despite market weakness
Despite a nearly 4% decline in the Nifty 50 over three months, several Nifty Smallcap 250 stocks have rallied sharply. Cupid led with 66% gains, followed by Sterlite Technologies and Welspun Corp, highlighting pockets of resilience amid market volatility.
Finकर Dashboard
Connect your accounts, track total net worth, and receive smart analytics triggers inside a unified monitoring hub.

HDFC Bank Q2 Results: Net profit rises 5% YoY to Rs 19,510 crore; NII grows 10%
HDFC Bank Q2 Results: India’s largest private lender HDFC Bank on Saturday reported a net profit of Rs 19,509 crore for the second quarter of FY27, marking a 4.6% year-on-year jump from Rs 18,641 crore posted in the same period last year.
DeepSeek: DeepSeek v4.1 Flash 1017
Article URL: https://openrouter.ai/deepseek/deepseek-v4.1-flash-1017 Comments URL: https://news.ycombinator.com/item?id=50129121 Points: 120 # Comments: 9
Crypto’s leverage machine finds new life beyond Bitcoin bets
Despite a decline in crypto trading activities, there is a rising interest in traditional assets among investors. Open interest in real-world asset contracts has increased to $9 billion, claiming 14% of total volume. The transition marks a significant change in the derivatives markets as crypto inroads are being utilized for traditional trading. This shift indicates a maturation of the digital asset space, making it more accessible to mainstream investors.
Crypto’s leverage machine finds new life beyond Bitcoin bets
Despite a decline in crypto trading activities, there is a rising interest in traditional assets among investors. Open interest in real-world asset contracts has increased to $9 billion, claiming 14% of total volume. The transition marks a significant change in the derivatives markets as crypto inroads are being utilized for traditional trading. This shift indicates a maturation of the digital asset space, making it more accessible to mainstream investors.

Reliance Jio IPO: From Dhirubhai Ambani's 1977 listing to Akash Ambani's mega issue - what's changed? Gen Z connect!
Jio Platforms plans a roughly $3.2 billion IPO, potentially India’s largest, at a valuation near $108 billion. The offering will test investor appetite for Reliance’s digital business as younger investors scrutinize its valuation, profitability and growth prospects.
DeepSeek-v4.1-Flash-1017
Article URL: https://huggingface.co/deepseek-ai/DeepSeek-V4.1-Flash-1017 Comments URL: https://news.ycombinator.com/item?id=50129045 Points: 114 # Comments: 40

Axis Bank Q2 Results: Net profit jumps 38% YoY- Check asset quality, stock trend, and other key highlights
Axis Bank reported a 38% year-on-year rise in Q2 FY27 net profit to ₹7,003 crore. Net interest income increased 12% to ₹15,371 crore, while net interest margin was 3.36%. Gross and net NPA ratios fell to 1.16% and 0.35%, respectively.
Axis Bank Q2 Results: Net profit jumps 38% YoY to Rs 7,003 crore, NII rises 12%
Axis Bank Q2 Results: Private lender Axis Bank on Saturday reported a net profit of Rs 7,003 crore for the second quarter of FY27, marking a jump of 38% from Rs 5,089 crore posted in the corresponding quarter of the previous financial year.

Stock market holiday on Dussehra 2026? Are NSE, BSE open or closed for trading on October 20 Tuesday? Calendar
Indian markets will be closed on Tuesday, October 20, for Dussehra, with trading also shut on November 10 and 24 and December 25.
F&O Talk: Nifty’s break above 23,450 could push index to 23,650; Sudeep Shah picks Tech Mahindra, TCS strategy
SBI Securities’ Sudeep Shah sees scope for Nifty’s recovery if it holds 22,750, with IT, private banks and media leading. He flags key resistance levels, banking earnings, improving FII flows and continued large-cap outperformance, while warning that a durable reversal remains unconfirmed.
8 small, midcap stocks with upside potential of up to 50%. How many are in your portfolio?
PL Capital remains cautious after the Nifty’s eight-week losing streak, warning against expectations of a V-shaped recovery. Despite market uncertainty, the brokerage favours eight small and midcap stocks, including CESC, Amber Enterprises and Healthcare Global, citing potential upside of 13-50%.

Paytm shares rally 50% in 6 months, but Nomura sees 33% more upside, initiates with 'buy'; check target price, rationale
Nomura initiated coverage of Paytm with a Buy rating and a ₹2,250 target, implying 33% upside. It expects rapid earnings growth, driven by digital payments, merchant lending, cost efficiencies and new revenue streams. Key risks include competition and deteriorating lending asset quality.
Concurrent Gainers: 15 stocks gain for 5 days in a row
The Sensex gained 3.11% during October 12–16, while 15 BSE 500 stocks posted consecutive gains. Tata Elxsi led with 23%, followed by KPIT Technologies at 16%.
Jio IPO’s grey market hints at 20% listing pop. What are Emkay, SBI Securities saying?
Jio Platforms’ Rs 30,200 crore IPO commands a grey market premium of Rs 221, suggesting nearly 20% listing gains. Emkay Global and SBI Securities highlight its telecom leadership, earnings growth, digital expansion and technology strengths, while flagging regulatory, competitive and financial risks.
Brent crude oil prices hit $110 for first time since May as Iran attacks continue, Ukraine eyes Russia energy infra
Brent crude surpassed $110 per barrel as escalating attacks around the Strait of Hormuz and renewed Russia-Ukraine hostilities heightened global supply concerns. WTI also surged, recording weekly gains above 10%. Goldman Sachs warned prices could reach $120 if shipping disruptions worsen, while easing tensions could bring crude towards $80.
AI fears are rocking markets. The brave should buy the dips.
There are fundamental reasons to be concerned about the AI trade right now, but other concerns are running the show.
ET Alpha Wealth Summit 2.0 | Why alternatives are becoming essential for wealth creation beyond stocks and bonds, says Rahul Jain
Nuvama Wealth Management’s Rahul Jain says alternative investments can diversify portfolios through private markets, AIFs, private credit, REITs and InvITs. He recommends evaluating risk before returns and taxes, while considering global equities and liquidity constraints when determining portfolio allocations.
Trump's Russia diesel deal may offer Putin more than money — and spell trouble for Ukraine
Trump's diesel deal may do little for Russia's finances, but it raises bigger questions about Ukraine's leverage, U.S. support and Putin's next moves.
Why India's steel demand is defying global weakness
India’s steel prices are rising despite weak global markets, supported by infrastructure spending, manufacturing growth and higher input costs. While Chinese oversupply pressures international prices, robust domestic consumption and capacity utilisation underpin India’s outlook, with cheaper imports remaining a key risk.

Dividend alert: IRFC, Tech Mahindra, ICICI Prudential AMC, among 11 stocks to watch next week: Check record date, payout
Dividend payouts announced by 11 companies range from ₹0.50 to ₹30 per share, with record dates scheduled for October 21–23, 2026. ICICI Prudential Asset Management Company offers the highest payout. Record dates and settlement rules determine eligibility.
Some companies give AI to everyone. This CEO is doing the opposite
Paysend CEO Ben Chisell limits AI tools to top performers as other U.K. companies push broader workplace rollouts.
$60 billion in 6 weeks: RBI's rupee defence comes at a cost
Reserve drain Forex reserves fall to $726 b on Oct 9 from $785.7 b on Sept 4, with latest reporting week alone showing a depletion of $8.58 b
AI bubble burst may trigger 2008-like banking crisis, says Gary Marcus
In a recent discussion, Gary Marcus raised critical flags about OpenAI's fiscal responsibilities as the stock market faces instability. He warned that the demise of leading AI firms could trigger extensive financial repercussions. Notably, Marcus compared the current climate to WeWork's disastrous decline, suggesting that Microsoft might pick up OpenAI at a bargain.
IT's time to celebrate when chips are down; Nifty IT soars 11.7% to log biggest weekly rally since 2008
The Indian IT sector experienced an impressive surge, achieving its highest weekly increase in 18 years, driven by unexpectedly strong quarterly results from companies like HCLTech. The Nifty IT index jumped 11.7%, amidst falling semiconductor stock prices in Asia. Furthermore, the rupee showed notable strength, closing below the 95-mark for the first time in 38 days, reflecting the effective measures implemented by the Reserve Bank of India.

Swiggy share price: Down 50% in 1 year; can food delivery stock recover? Should you buy the dip? Check target, stop-loss
Swiggy’s improving food-delivery profitability and plans to reduce Instamart losses have prompted Anand Rathi to retain a Buy rating and ₹310 target, implying about 35% upside from ₹230. However, the stock’s weak chart signals caution.
Dollar heads for weekly loss as Fed hike bets fade, AI jitters linger
This week, the dollar faced a notable drop due to decreased expectations for interest rate increases from the Federal Reserve. Federal officials' remarks have led to steadying Treasury yields, which in turn weakened the dollar's position. Concurrently, the euro and yen gained ground, with the euro nearing a weekly rise. Investors are increasingly wary of fiscal risks, especially as shifts in economic conditions unfold.
Gold set for a weekly drop as traders assess Fed signals
Gold prices have held steady this week, though they are set to close lower overall as market participants assess the potential for a Federal Reserve rate hike. Spot gold recorded a modest drop of 0.1%, while futures displayed slight gains amid market hesitance. Discussions among Federal Reserve officials vary regarding the strength of the economy and inflation predictions.
Global markets: Stocks slip as dollar heads for weekly loss
In a week fraught with concerns over escalating interest rates and financial complications tied to AI, global stock indices saw moderate declines. While the S&P 500, Nasdaq, and Dow Jones recorded losses, the Dow managed to post a weekly gain. In contrast, European markets, led by London's FTSE 100, experienced a positive turn.
Wall Street Week Ahead: As AI rally wobbles, stock market's spotlight turns to earnings
Investor confidence in the market is wavering due to recent declines in AI-linked stocks and semiconductor firms. Upcoming quarterly results from major players, including Meta Platforms, are being closely monitored by investors. Analysts are watching whether hyperscalers can sustain profitability amid significant capital expenditures on AI infrastructure. The performance of companies such as Tesla and SpaceX will also influence market sentiment.
Jio’s $3.2 billion IPO tests Ambani appeal with young Indians
Jio’s $3.2 billion IPO tests Ambani appeal with young Indians
Butlerian Jihad
Article URL: https://dune.fandom.com/wiki/Butlerian_Jihad Comments URL: https://news.ycombinator.com/item?id=50127274 Points: 104 # Comments: 47

Sunil Singhania makes a fresh entry in this defence stock
Sunil Singhania has picked up a stake in this defence stock. Read on to know his new position.

Apple Bans 'Nudify' AI Apps After Grok Deepfake Scandal
[Apple](https://www.apple.com) just rewrote its App Store rulebook to explicitly ban so-called 'nudify' apps that use AI to generate nonconsensual intimate images. The policy update comes after months of pressure following the Grok deepfake controversy earlier this year, when users exploited X's AI tool to create sexualized images of minors. It's a rare moment of Apple tightening the screws on AI apps amid growing concerns about deepfake abuse and digital harassment. [Apple](https://www.apple.com) is drawing a hard line on AI-generated harassment.

Replit Dumps Anthropic for OpenAI, Citing Cost Pressures
Replit CEO Amjad Masad just dropped a bombshell at TechCrunch Disrupt: the coding platform hasn't been working with Anthropic for months. The revelation comes as a surprise to an industry that watched Replit announce an [OpenAI](https://openai.com) partnership in August without any hint it was ditching Claude. Cost pressures drove the decision, Masad said, marking another win for [OpenAI](https://openai.com) in the battle for developer platform partnerships. [Replit](https://replit.com) just confirmed what it carefully avoided saying for months: it's done with [Anthropic](https://anthropic.
5 midterm money takeaways: Democrats have candidate cash. Republicans have Elon Musk
Democrats outraise Republicans in key Congress races as Elon Musk funds Ken Paxton in Texas and GOP groups aligned with Trump.
Replit is no longer working with Anthropic, CEO says
Replit CEO and co-founder Amjad Masad made the comments during TechCrunch Disrupt 2026.

Foreign Holdings of US Treasuries Rise From Almost One-Year Low
Foreign holdings of US Treasuries rose in August from the lowest level since October 2025, led by increases in the stockpiles of Canada and Belgium.

Meta Business Accounts Now Opt Into AI Data Scraping
[Meta](https://meta.com) just changed the rules for millions of business accounts, and legal experts say there's no way out. The company's updated terms of service now include provisions that effectively consent business account holders to having their data scraped for AI training purposes. The move puts small businesses, agencies, and enterprise users in a bind - keep your business presence on Facebook and Instagram, or lose access to Meta's 3 billion users while trying to protect your data. [Meta](https://meta.
Why did CoreWeave stock get crushed this week? Look to this corner of the debt market for clues
CoreWeave’s bond yields and credit default swaps have surged as its stock sells off. Here’s what those credit signals mean for stock investors.
I never authorized an integration that scans my secrets
Article URL: https://github.com/home-assistant/home-assistant.io/issues/49314 Comments URL: https://news.ycombinator.com/item?id=50124251 Points: 104 # Comments: 51

ITC sets board meeting date to declare Q2 results 2026; net profit may decline due to cigarette taxation — share outlook
Q2 results 2026: ITC informed about the board meeting date to declare Q2FY27 earnings in an exchange filing on Friday
US stocks: US market ends down sharply; worries about AI trade and high oil prices weigh
Wall Street faced a sharp decline on Friday as AI-related technology stocks came under renewed pressure. Concerns regarding debt-laden AI infrastructure companies affected investor sentiment heading into the weekend. Additionally, a rise in oil prices fueled market fears about economic stability and rising borrowing costs. The S&P 500, Dow Jones, and Nasdaq all recorded substantial losses amid these uncertainties.
Katie Zacharia Was Linked to an AI Rare-Earths Startup. It’s Even Weirder Than It Sounds
The short-lived White House press secretary was listed as an adviser to a Kristi Noem-linked company that aims to use AI for mining. Both the company and she say she never worked there.
FLUX 3 Image Klein
Article URL: https://bfl.ai/blog/flux-3-image-klein Comments URL: https://news.ycombinator.com/item?id=50123580 Points: 101 # Comments: 24
Brent oil touches $110 as Iran escalates Hormuz attacks, Ukraine vows to hit Russian refineries
U.S. crude oil prices rose sharply Friday as Iran escalated attacks in the Strait of Hormuz this week.

Funding Markets Diverge as T-Bills Cheapen, Overnight Repo Calm
Treasury-bill yields have risen sharply as a wave of new issuance tests investor demand, posing a threat to the stability of overnight funding markets.

Stocks slip as dollar heads for weekly loss
GLOBAL-MARKETS/ (UPDATE 5):GLOBAL MARKETS-Stocks slip as dollar heads for weekly loss
Wall Street's fear gauge is ripping. Traders see it going even higher
The sell-off in AI-related stocks pushed the VIX above 22 for the first time in four months. A cluster of trades suggests it could go even higher.

Arabica coffee touches one-month high as stocks remain critically low
GLOBAL-SOFTS/ (UPDATE 1):SOFTS-Arabica coffee touches one-month high as stocks remain critically low

Apple Enters Smart Home Hardware Race With Home Collection
After spending more than a decade telling other companies to build smart home devices for its platform, [Apple](https://www.apple.com) just became its own competitor. The company launched the Apple Home Collection this week - a full lineup of cameras, thermostats, sensors, a smart door lock, and video doorbell codeveloped with [LG Electronics](https://www.lg.com) and [Schneider Electric](https://www.se.com). The move arrives alongside [HomeView](https://www.theverge.
How the Claude Code team does code review
Article URL: https://claude.dev/blog/solving-code-review-at-anthropic/ Comments URL: https://news.ycombinator.com/item?id=50122951 Points: 113 # Comments: 102
You could have invented transformers from memory
Article URL: https://alexwang.ai/posts/associative-memory/ Comments URL: https://news.ycombinator.com/item?id=50122878 Points: 101 # Comments: 25
Claude reveals ECDSA curve origins
Article URL: https://www.anthropic.com/research/ecdsa-curve-origins Comments URL: https://news.ycombinator.com/item?id=50122800 Points: 164 # Comments: 66
Apple’s $1,999 iPhone Duo puts the company's status-symbol power to the test
Apple’s $1,999 iPhone Duo is drawing early demand as analysts assess whether the foldable can lift iPhone pricing and revenue.
Big US bank stocks head for longest weekly losing streak since 2008
Major US banks are experiencing their longest weekly losing streak since the 2008 financial crisis, driven by mixed quarterly earnings and rising inflation. The KBW Bank Index has fallen about 13% since its August peak, continuing a trend of losses. Concerns about artificial intelligence disrupting financial services contribute to the negative sentiment toward the sector. Analysts highlight challenges involving elevated interest rates potentially slowing economic growth.
Yes Bank flags 250-bps impact on core capital ratio after Supreme Court upholds AT-1 bond write-off ruling
Yes Bank said its Common Equity Tier 1 capital ratio could fall by about 250 basis points after the Supreme Court upheld a ruling against the 2020 write-down of ₹8,415 crore in AT-1 bonds. The bank expects its overall Tier 1 ratio to remain at 14% and is reviewing its legal options.

Top 3 stocks to buy: Bajaj Finance, Dr Reddy's Lab, Grasim Industries by Sumeet Bagadia | Target price, stop-loss
Nifty prediction: Sumeet Bagadia believes the Nifty 50 RSI has improved to 52.81, well above its average of 34.70, indicating strengthening bullish momentum

Indian IT stocks post best weekly gain in 18 years amid global AI sell-off
This comes as AI sell-off drives investors towards the country's software firms
Llama.cpp on a jailbroken PS5: run any GGUF model natively on the console
Article URL: https://github.com/cobanov/PS5LM Comments URL: https://news.ycombinator.com/item?id=50122431 Points: 105 # Comments: 30

Sebi's IPO nod to Cult.fit, Eswari Global Metal, Sohan Lal Commodity
Zetwerk's IPO was subscribed 31% on Day 2, while the company raised ₹2,251 crore from anchor investors, including BlackRock and Goldman Sachs.
Trump says White House didn't order Starlink restrictions in Ukraine
Ukrainian officials complained this week that SpaceX had limited internet connectivity without advance notice.
The Austin Powers steamroller: How to trade CoreWeave's slow moving crisis
After a 27.5% drop from last Friday's close to this Thursday morning's 52-week lows, followed by a 17% rebound, equity traders holding CoreWeave are dazed.

India Inc's FY27 profit growth estimates dip 700 bps since February
Iran war-driven input cost pressures drag FY27 earnings growth forecast to 9.2% from 16.5% in February, while real estate bucks the trend

HFCL shares jump 277% in 2026 ahead of Reliance Jio IPO; Nuvama says buy rating. Check target price and Jio connection
Nuvama initiated coverage of HFCL with a Buy rating and a ₹380 target, citing its shift toward telecom and networking products, strong order book, investment plans and opportunities in data centers and defence.
Anthropic assigned highest junk credit rating in June
Article URL: https://www.ft.com/content/5a310aee-f555-4266-874c-b1b4db20186d Comments URL: https://news.ycombinator.com/item?id=50122112 Points: 107 # Comments: 29
Debt is eating up a bigger chunk of your raise, research shows
New research finds debt payments rose far faster than estimated real household income, absorbing about half of a one-earner household's gains.

Anthropic Opens Doors to Independent AI Auditors
[Anthropic](https://www.anthropic.com) just cracked open the black box. The AI safety company announced it's granting third-party auditors employee-like access to its systems, marking the first time a major AI lab has voluntarily embedded independent oversight into its operations. The move comes as [Anthropic appeals a Pentagon blacklist](https://www.techbuzz.ai/articles/anthropic-appeals-pentagon-ai-blacklist-in-federal-court) and faces mounting pressure to prove its safety credentials aren't just marketing talk. [Anthropic](https://www.anthropic.
eBay Restricts Listings of Radio Equipment, but Exempts Ham-Band-Only Gear
Article URL: https://www.arrl.org/arrlletterissue?issue=2026-10-15#eBay-Restricts-Listings-of-Radio-Equipment_-But-Exempts-Ham-Band-Only-Gear Comments URL: https://news.ycombinator.com/item?id=50122034 Points: 100 # Comments: 78
Designing more efficient quantum circuits with Claude
Article URL: https://www.anthropic.com/research/designing-efficient-quantum-circuits Comments URL: https://news.ycombinator.com/item?id=50121939 Points: 103 # Comments: 20
U.S. budget deficit swells to almost $2 trillion for fiscal 2026, up 12% in a single year
The Treasury Department published the U.S. budget deficit for the 2026 fiscal year.
Roundtables: A Conversation With the Creator of AI-Designed Viruses
Listen to the session or watch below Can AI design new life forms? In 2025, Stanford University PhD student Samuel King came up with a preliminary answer when he used a generative AI model to propose genetic blueprints for microscopic viruses. It isn’t yet an example of AI-generated life, but that could be next. Watch as senior AI reporter James O’Donnell interviews King about his work, being named one of MIT Technology Review’s Innovators Under 35 and new ways of seeing biology.
Chip selloff deepens Wall Street losses as doubts grew over AI returns
A significant selloff in semiconductor stocks affected major US indexes amid rising concerns regarding AI investment returns. The Nasdaq 100 dropped by 1.8%, continuing its longest losing streak since 2008. Market participants are questioning if AI infrastructure investments will yield profitable returns despite strong demand for chips. Federal Reserve Chairman Kevin Warsh maintained a neutral stance on interest rates during discussions at the IMF meetings.
India becomes the latest country to report rogue AI agent activity
The agents got in through credentials and connection settings left exposed in app configurations, public code repositories, and overly permissive cloud roles.
NBA tightens betting rules, develops AI to flag suspicious wagers
The NBA is tightening restrictions on bets and deploying AI to help identify suspicious wagering, according to two documents obtained by CNBC.
Trump says new White House press secretary Katie Zacharia should 'reconsider' job
Trump made the remarks about Zacharia before heading to Georgia for a rally aimed at boosting Republicans in the final days before the midterm elections.
90% of US working hours are spent on tasks not covered well by AI benchmarks
Article URL: https://www.mercor.com/research/labor-index/benchmark-map/ Comments URL: https://news.ycombinator.com/item?id=50121179 Points: 106 # Comments: 77

Reliance-backed Jio Platforms IPO: ₹1 lakh crore gains for Meta, Google in ₹30,213 cr issue by Mukesh Ambani firm?
Meta and Google could hold nearly ₹1 lakh crore in paper gains from their Jio Platforms investments, with estimated returns of about 129%.
Here's who Netflix just brought in to run content — and what it means for the streamer
Peter Rice brings a wealth of experience in TV and film, including scripted and unscripted shows, live sports, prestige television and theatrical distribution.
/dev/null: social network for developers
Article URL: https://dev-null.sh Comments URL: https://news.ycombinator.com/item?id=50121004 Points: 101 # Comments: 95

Why Robotics Still Hasn't Hit Its ChatGPT Moment
The robotics industry isn't anywhere near its breakthrough moment, despite the hype around AI-powered humanoids and foundation models. Amulya Vishwanath, who spent seven years leading product marketing for [Nvidia's](https://www.nvidia.com) robotics platforms before jumping to venture capital, argues the sector is still in its "Lego era" - rebuilding basic building blocks like actuators, robotic hands, software, and safety standards from scratch.
Desire to Move Permanently to U.S. at New Low
Article URL: https://news.gallup.com/poll/708614/desire-migrate-drops-new-low.aspx Comments URL: https://news.ycombinator.com/item?id=50120664 Points: 111 # Comments: 82

₹30 dividend: ICICI Prudential AMC dividend record date ahead! Check yield, payout history, stock performance
ICICI Prudential AMC has declared an interim dividend of ₹30 per share for FY27, with October 21, 2026, set as the record date. Investors must own shares by October 20 to qualify. The stock closed 0.90% lower at ₹2,811.75 on Friday.

